for Health Care Providers

Table 12. Management strategy of HCC based on CTP class, size, and performance status


CTP, Child-Turcotte-Pugh; HCC, hepatocellular carcinoma, HVPG; hepatic venous pressure gradient; PEI, percutaneous ethanol injection; PS, performance status; RFA, radiofrequency ablation.
CTP A, PS 0	Single HCC <2 cm	HVPG <10 mm Hg and bilirubin <1.5 mg/dl Surgical resection
CTP A, PS 0	Single HCC <2 cm	Varices/collaterals or HVPG >10 mm Hg or bilirubin >1.5 mg/dl Liver transplant evaluation RFA/PEI
CTP A-B, PS 0-2	Single HCC 2-5 cm	HVPG <10 mm Hg and bilirubin <1.5 mg/dl Surgical resection
	Single HCC 2-5 cm	Varices/collaterals or HVPG >10 mm Hg or bilirubin >1.5 mg/dl Liver transplant evaluation RFA/PEI
	2 or 3 HCC masses <3 cm (the largest)	Liver transplant evaluation Radiofrequency ablation
	Intermediate stage (multinodular , PS 0)	Transarterial chemoembolization
	Advanced stage (portal invasion, metastases)	Sorafenib
CTP C, PS >2	Terminal stage	Symptomatic treatment