for Health Care Providers
Supplemental Table 1: Treatment Monitoring Guidelines for Patients on Peginterferon-Ribavirin plus or minus Protease Inhibitor (Boceprevir or Telaprevir)
| Week | |||||||||
|---|---|---|---|---|---|---|---|---|---|
*Intervals may need to be increased based on patient tolerance and response to treatment in patients with significant declines in blood counts, renal insufficiency, diabetes, cirrhosis or other indications. **Recommended for all patients at baseline and periodically during antiviral treatment in patients with diabetes, hypertension or as needed for visual complaints. | |||||||||
| Necessary | 0 | 2 | 4 | 8 | 12 | 24 | Every 4-weeks Thereafter | End-of-Treatment | 24 weeks Post-treatment |
| HCV RNA | √ | √ | √ | √ | √ | Follow Algorithm for additional timepoints | √ | √ | |
| CBC with differential | √ | √ | √ | √ | √ | √ | √* | √ | |
| Liver function tests | √ | √ | √ | √ | √ | √ | √* | √ | |
| Psychiatric/Substance Use Screening | √ | √ | √ | √ | √ | √ | √* | ||
| Renal panel | √ | √ | √ | * | |||||
| Glucose | √ | √ | √ | * | |||||
| TSH | √ | √ | √ | * | |||||
| Uric acid (if on telaprevir) | √ | √ | √ | √ | √ | √ | * | √ | √ |
| Pregnancy test | √ | √ | √ | √ | √ | √ | √ | √ | |
| Recommended | |||||||||
| Fundoscopic Exam** | √ | ||||||||
| Urine Toxicology Screen | √ | ||||||||

