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Viral Hepatitis


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Hepatitis C Treatment Considerations

for Veterans and the Public

Chronic Hepatitis C Virus (HCV) Infection: Treatment Considerations


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This revision (March 28, 2016) incorporates updates to treatment regimens for chronic hepatitis C virus (HCV) infection, genotype 1, 2, 3, or 4. The Introduction has been revised to include a new section titled "Interpretation of Resistance Associated Polymorphisms." Additional revisions include updates on drug-drug interactions to provide clinicians with guidance on the concomitant use of HCV drugs and other drugs, including HIV antiretroviral agents (Appendix A, Tables A4 and A5). Information on HCV resistance genotyping and sample reports have been included (Appendices B and C). The Panel continues to recommend that HIV/HCV-coinfected patients receive the same HCV antiviral regimens as HCV-monoinfected patients.