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Virologic Response Rates in the ACTG 5071 Study

for Health Care Providers

Table 7. Virologic Response Rates in the ACTG 5071 Study

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INF alfa-2a 6 MIU. tiw x 12 wk, then 3 MIU. tiw x 36 wk + RBV 600 mg increasing to 1,000 mg as tolerated over 6 wkPeg INF alfa-2a (PEGASYS) 180 µg/wk x 48 wk + RBV 600 mg increasing to 1,000 mg as tolerated over 6 wk
* p < 0.001 versus IFN + RBV; ** p = 0.03 versus IFN + RBV.
n = 67n = 66
ETR (Overall) 12% 41%*
Genotype 1 6% 29%
Non-genotype 1 33% 80%
SVR (Overall) 12%27%**
Genotype 16% 14%
Non-Genotype 1 33% 73%