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Table 8. Virologic Response Rates in the APRICOT Study
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| INF alfa-2a 3 MIU. tiw + RBV 800 mg/day x 48 wk | Peg INF alfa-2a (PEGASYS) 180 µg/wk + placebo x 48 wk | Peg INF alfa-2a (PEGASYS) 180 µg/wk + RBV 800 mg/day x 48 wk | |||||
|---|---|---|---|---|---|---|---|
| *p = 0.0078 versus IFN + RBV; ** p < 0.0001 versus IFN + RBV, p < 0.0001 versus PEG only. | |||||||
| n = 285 | n = 286 | n = 289 | |||||
| ETR (Overall) | 14% | 33% | 49% | ||||
| Genotype 1 | 8% | 21% | 38% | ||||
| Non-Genotype 1 | 27% | 57% | 64% | ||||
| SVR (Overall) | 12% | 20%* | 40%** | ||||
| Genotype 1 | 7% | 14% | 29% | ||||
| Non-Genotype 1 | 20% | 36% | 62% | ||||
