Guidelines and Best Practices

Treatment

• Management and Treatment of Hepatitis C Virus Infection
  Recommendations from the Department of Veterans Affairs Hepatitis C Resource Center Program and the National Hepatitis C Program Office, October 2006
  • Hepatitis C Management and Treatment Algorithm
    From the VA Hepatitis C Resource Center Program, 2010
  • Hepatitis C Quicknotes
    Abbreviated version of the 2006 recommendations
• Guidance for Hepatitis C Treatment Monitoring
  Monitoring Patients on Pegylated Interferon + Ribavirin ± Protease Inhibitor (Boceprevir or Telaprevir), March 2012
• An Update on Treatment of Genotype 1 Chronic Hepatitis C Virus Infection: 2011 Practice Guideline by the American Association for the Study of Liver Diseases
  Ghany MC, Nelson, DR, Strader, DB, et al. Hepatology, Vol. 54, No. 4, 2011, 1433-1444.
• Hepatitis C Treatment-Related Anemia and Neutropenia
  Criteria for Use documents for using granulocyte stimulating colony factor and recombinant erythropoietin for hepatitis C treatment-related anemia and neutropenia, from the VHA Pharmacy Benefits Management Strategic Healthcare Group and Medical Advisory Panel

Prevention and Transmission

• Recommended Adult Immunization Schedule: United States, 2012
  Morbidity and Mortality Weekly Report: February 3, 2012 / 61(04);1-7.
• Recommendations for prevention and control of hepatitis C virus (HCV) infection and HCV-related chronic disease
  Morbidity and Mortality Weekly Report: Recommendations and Reports, October 16, 1998
• Updated U.S. Public Health Service guidelines for the management of occupational exposures to HBV, HCV, and HIV and recommendations for postexposure prophylaxis
  Morbidity and Mortality Weekly Report: Recommendations and Reports, June 29, 2001

Testing and Counseling

• Hepatitis C Testing and Prevention Counseling Guidelines for VA Health Care Practitioners
  Guidelines to help providers assist Veterans in identifying their hepatitis C status, provide education, and help facilitate behavior changes that will reduce their risk of acquiring or transmitting the hepatitis C virus, 2001
  • Hepatitis C Virus Antibody Screening Flow Chart
    Screening flow chart for the Veteran population
• CDC: Guidelines for laboratory testing and result reporting of antibody to hepatitis C virus
  Morbidity and Mortality Weekly Report: Recommendations and Reports, February 7, 2003

Clinical Management

• Diagnosis, management, and treatment of hepatitis C: an update.
  Ghany MG, Strader DB, Thomas DL, Seeff LB; American Association for the Study of Liver Diseases. Hepatology. 2009 Apr;49(4):1335-74.
• Liver biopsy.
  AASLD Position Paper; Rockey DC, Caldwell SH, Goodman ZD, et al. Hepatology. 2009 Mar;49(3):1017-44.

HIV Coinfection

• ARV Interactions with HCV Protease Inhibitors
  Drug interactions table from HIV InSite.
• Management and Treatment of Hepatitis C Virus Infection in HIV-Infected Adults
  VA Hepatitis C Resource Center and National Hepatitis C Program Office, September 1, 2005
• British HIV Association guidelines for the management of coinfection with HIV-1 and hepatitis B or C virus 2010.
  Brook G, et al. HIV Med. 2010 Jan;11(1):1-30.

Cirrhosis

• Management and Treatment of Patients with Cirrhosis and Portal Hypertension, May 2009
  Treatment recommendations for cirrhosis based on evidence in the literature, as well as on the results of the most recent consensus conferences
  • Cirrhosis Quicknotes
    Abbreviated version of the 2009 recommendations
• Management of Adult Patients With Ascites Due to Cirrhosis
  AASLD Practice Guideline. Runyon, BA. Hepatology. 2009 Jun;49(6):2087-107.

Hepatocellular Carcinoma

• Management of Hepatocellular Carcinoma: An Update
  AASLD Practice Guideline; Bruix J and Sherman M. Hepatology. 2011 Mar;53(3): 1020-22.
• Management of Hepatocellular Carcinoma (HCC)
  Clinician's Guide from the Hepatitis C Resource Centers, 2009
  • Hepatocellular Carcinoma Quicknotes
    Abbreviated version of the 2009 recommendations
  • Hepatocellular Carcinoma Diagnostic and Treatment Algorithm
    From the VA Hepatitis C Resource Center Program, 2010
• Clinical Management of Hepatocellular Carcinoma. Conclusions of the Barcelona-2000 EASL Conference
  Bruix J, et al. Journal of Hepatology. 2001 35:421-430.

Hepatitis A and B

• Chronic Hepatitis B: Update 2009 (AASLD Practice Guidelines).
  Lok, AS and McMahon, BJ. Hepatology. 2009 Sep;50(3):661-2.