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Viral Hepatitis

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Hepatitis C Quicknotes: Endpoints of HCV Therapy

for Health Care Providers

Endpoints of HCV Therapy

  1. RVR:
    • HCV RNA <50 IU/mL at week 4 into treatment
  2. EVR:
    • >2 log 10 reduction from baseline HCV RNA at week 12 of treatment
  3. ETR:
    • Undetectable HCV RNA at completion of treatment
  4. SVR:
    • Undetectable HCV RNA at week 24 after completion of treatment
  5. Relapse:
    • Undetectable viremia during or at the end of treatment but HCV RNA is detectable after treatment is stopped
  6. Nonresponse:
    • Detectable HCV RNA throughout treatment

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