Hepatitis B Virus Tests and Interpretation - Hepatitis B
| Test | Susceptible | Immune due to Successful Vaccination | Immune due to Resolved infection | Acute HBV | Prior HBV and isolated HBcAb+ |
|---|
| *Test is only needed if patient is HBsAg positive or there is suspicion of occult HBV. |
| HBV surface antigen (HBsAg) | Neg | Neg | Neg | Pos | Neg |
|---|
| HBV surface antibody (HBsAb) | Neg | Pos | Pos | Neg | Neg |
|---|
| HBV core antibody IgG (HBcAb IgG) | neg | Neg | Pos | Pos | Pos |
|---|
| HBV core antibody IgM (HBcAb IgM) | Neg | Neg | Neg | Pos | Neg |
|---|
| HBeAg* | Not applicable | Not applicable | Not applicable | Neg | Neg |
|---|
| HBeAb* | Not applicable | Not applicable | Not applicable | Neg | Pos |
|---|
| HBV DNA* | Not applicable | Not applicable | Not applicable | Neg or Pos | Neg |
|---|
| ALT* | Not applicable | Not applicable | Not applicable | Elevated | Typically Normal |
|---|
| Test | Occult HBV, with loss of HBsAg | Chronic Inactive HBV | Chronic HBV, e-Ag positive | Chronic HBV, e-Ag negative | Reactivation of Chronic HBV |
|---|
| *Test is only needed if patient is HBsAg positive or there is suspicion of occult HBV. |
| HBsAg | Neg | Pos | Pos | Pos | Pos |
|---|
| HBV surface antibody (HBsAb) | Neg | Neg | Neg | Neg | Neg |
|---|
| HBV core antibody IgG (HBcAb IgG) | Pos | Pos | Pos | Pos | Pos |
|---|
| HBV core antibody IgM (HBcAb IgM) | Neg | Neg | Neg | Neg | Neg |
|---|
| HBeAg* | Neg | Neg | Pos | Neg | Pos or Neg |
|---|
| HBeAb* | Pos | Pos | Neg | Pos | Pos or Neg |
|---|
| HBV DNA* | Pos | Neg or Low Level | Pos | Pos | Pos |
|---|
| ALT* | Variable (Normal-Elevated) | Normal | Variable (Normal-Elevated) | Variable (Normal-Elevated) | Elevated |
|---|
