Attention A T users. To access the menus on this page please perform the following steps. 1. Please switch auto forms mode to off. 2. Hit enter to expand a main menu option (Health, Benefits, etc). 3. To enter and activate the submenu links, hit the down arrow. You will now be able to tab or arrow up or down through the submenu options to access/activate the submenu links.

Viral Hepatitis and Liver Disease

Menu
Menu
Quick Links
Veterans Crisis Line Badge
My healthevet badge
 

HBeAg-Positive Patients with Elevated ALT and Without Cirrhosis

for Health Care Providers

Monitoring Patients Not on Treatment - Hepatitis B

HBeAg-Positive, Elevated ALT, Without Cirrhosis

HBeAg-Positive Patients with Elevated ALT and Without Cirrhosis Flow Chart


* Cut off (upper limit of normal = ULN) of a normal ALT ≤ 35 U/L for males and ≤ 25 U/L for females is recommended to guide management decision

** Additionally monitor HBeAg every 6-12 mo

*** Other factors in decision to treat elevated ALT that is < 2x upper limit and HBV DNA is < 20,000: Age > 40, family history of HCC, previous treatment history, presence of extrahepatic manifestations, presence of cirrhosis

Adapted from: Terrault NA, et al. Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance. Hepatology. 2018;67(4):1560-1599. doi: 10.1002/hep. 29800.