Non-Alcoholic Fatty Liver Diagnosis - Viral Hepatitis and Liver Disease
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Viral Hepatitis and Liver Disease


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Non-Alcoholic Fatty Liver Diagnosis

for Health Care Providers

Diagnosis - Non-Alcoholic Fatty Liver

Identifying non-alcoholic fatty liver disease

Does this patient have NAFLD? In patients with metabolic syndrome, obesity, and/or diabetes, NAFLD is likely present if there is:

  • fatty liver on imaging
  • modest or no alcohol use, whether or not ALT is elevated
  • no hepatitis B or C or secondary causes, such as parenteral nutrition, or culprit medications (e.g., corticosteroids, methotrexate, diltiazem, amiodarone, tamoxifen, highly active antiretroviral therapy)

Metabolic syndrome

Metabolic syndrome is diagnosed by 3 of the following 5 criteria:

  • blood pressure ≥130 mmHg systolic or ≥85 mmHg diastolic (or on treatment)
  • fasting glucose ≥100 mg/dl (or on treatment)
  • triglycerides ≥150 mg/dl (or on treatment)
  • HDL cholesterol <40 mg/dl in men or <50 mg/dl in women (or on treatment)
  • waist circumference ≥40 inches (102 cm) in men or ≥35 inches (88 cm) in women


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Practice Guidance from the American Association for the Study of Liver Diseases; Hepatology, 2018